Nature of science:
Developments in scientific research follow improvements in apparatus—fluorescent calcium ions have been used to study the cyclic interactions in muscle contraction. (1.8)
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Understandings:
- Bones and exoskeletons provide anchorage for muscles and act as levers.
- Synovial joints allow certain movements but not others.
- Movement of the body requires muscles to work in antagonistic pairs.
- Skeletal muscle fibres are multinucleate and contain specialized endoplasmic reticulum.
- Muscle fibres contain many myofibrils.
- Each myofibril is made up of contractile sarcomeres.
- The contraction of the skeletal muscle is achieved by the sliding of actin and myosin filaments.
- ATP hydrolysis and cross bridge formation are necessary for the filaments to slide.
- Calcium ions and the proteins tropomyosin and troponin control muscle contractions.
Applications and skills:
- Application: Antagonistic pairs of muscles in an insect leg.
- Skill: Annotation of a diagram of the human elbow.
- Skill: Drawing labelled diagrams of the structure of a sarcomere.
- Skill: Analysis of electron micrographs to find the state of contraction of muscle fibres.
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Aims:
- Aim 7: Use of grip strength data loggers to assess muscle fatigue.
- Aim 7: Use of animations to visualize contraction.
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Guidance:
- Elbow diagram should include cartilage, synovial fluid, joint capsule, named bones and named antagonistic muscles.
- Drawing labelled diagrams of the structure of a sarcomere should include Z lines, actin filaments, myosin filaments with heads, and the resultant light and dark bands.
- Measurement of the length of sarcomeres will require calibration of the eyepiece scale of the microscope.
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